First, remove the dentures from your mouth and place them under running water to wash away food particles on or under the surface or stuck between the denture teeth. Then use a mild soap and soft toothbrush for further cleaning.
Do not use regular toothbrushes, electric toothbrushes, or regular toothpaste since they are too abrasive for the dentures. After cleaning, make sure to rinse it. Also, don’t forget to clean your gums and residual natural teeth with fluoridated toothpaste and a soft toothbrush when the dentures are out of your mouth.